Blood pressure in Circulatory Insufficiency

Blood pressure in Circulatory Insufficiency can be either high, low or normal depending on the systemic resistance to blood flow.

Acute Circulatory Insufficiency with High Blood Pressure

The flow of blood is dependent on the pressure driving it vs the resistance it encounters. The functional problem when blood pressure is high is that the resistance to the flow of blood is generally impaired. Essential Hypertension is a permanently high resistance to blood flow due to diffuse and widespread vascular disease. This resistance to blood flow is difficult to impossible to measure under most circumstances. Instead of measuring systemic vascular resistance, the actual physical disease, blood pressure is measured and assumed to be indicative of the increased resistance. Most of the time the increased resistance is overcome by the increased blood pressure.

Acute Circulatory Insufficiency with Increases in Vascular Resistance

Symptoms due to reduced blood flow and cardiac output can develop when systemic vascular resistance. This mechanism of shock is not what is usually thought of. Most of the time it is attributed to loss of cardiac function. Spikes in vascular resistance can develop from the use of drugs with vasoconstrictor properties such as methamphetamine. Other causes of increased vascular tone such as emotional or physical stress can also cause a sudden increase in vascular resistance due to sympathetic outflow. Stress and vasoconstrictor drugs can combine together to produce a greater effect. In cases where cardiac output is significantly impaired, anaerobic metabolism can develop leading to an acidemia from the production of lactic acid. The symptoms are a feeling of breathlessness and hyperventilation. It appears as if the individual has a breathing disorder.



It is also commonly thought that if the oxygen level in the arterial blood is adequate then the tissue will be adequately supplied. This omits the second step, oxygen has to be delivered. Elevated blood pressure is a clue that the resistance to blood flow is elevated. It is however, blood pressure and total peripheral resistance are not the same. Resistance and blood pressure are related by this equation, CO = BP/SVR. The poor circulation of blood due to elevated resistance will reduce the delivery of oxygen. This is perceived as dyspnea when combined with an acidemia produced by the production of lactic acid.

Acute Circulatory Insufficiency with Low Blood Pressure

Acute Circulatory Insufficiency can occur with low blood pressure. This typically occurs when there is an acute insult to the heart such as a large myocardial infarction. In this case the resistance may be normal or below normal. Circulatory Insufficiency may occur because the blood pressure is low and even as the resistance is not elevated insufficient flow occurs. Acute Circulatory Insufficiency is identified when anaerobic metabolism develops leading to an acidemia from the production of lactic acid. This is sometimes identified as pump failure. The cardiovascular nature of this syndrome is easier to appreciate than when blood pressure is elevated.